The June issue of the neuroscience journal Brain has an amazing cover showing “increasingly bizarre and menacing caricatures by an artist with frontotemporal lobar degeneration during the course of his illness”.
The caption reads:
From left, the first picture drawn many years before his illness; the middle pair in the first 2 years of dementia; and that on the right at least 3 years into the illness. Background: Gouache entitled ‘Unravelling Boléro’, showing de novo transmodal creativity comprising auditory to visual transformation, by a patient with primary progressive aphasia…
Mind Hacks 
Having a lack of denial to the point where you can illustrate your own deterioration makes for interesting art but I find it pretty grim. I’m also completely baffled by the use of pastels.
what’s the possibility that dementia is a result of a persons awareness of their diminishing relevance?
This is a painting from a woman by the name of Anne Adams. The drawings are so beautiful. There was a RadioLab episode on this woman, comparing her disease to Ravel, who actually had the same disease.