Psychotherapy with the Amish

Photo from Wikipedia. Click for sourceNPR has a fascinating segment on psychotherapist Jim Cates, who works with Amish youth who are experiencing the turbulent time of ‘Rumspringa‘ – a period when they get to experience non-Amish life so they can decide whether they want to commit to their parents’ culture and traditions.

The Amish are a community based around Anabaptist Christianity who, to varying degrees, refuse modern technology and the common social practices of North America.

However, during the time of Rumspringa, the youth are free to wear modern clothes, use technology, and may experiment with drink, drugs and sex – on the basis that the Amish want their youth to freely enter their tradition having had the opportunity to experience the alternative.

For some young people, this causes some difficulties, not least with some who encounter difficulties with drink, drugs or emotional adjustment and Jim Cates is a psychotherapist who helps the young people work through the issues.

He describes how he needs to take a radically different approach when conducting psychotherapy with Amish youth, owing to the markedly different way of thinking, particularly about the role of the individual in society.

Cates notes that while traditional American culture is individualist, Amish culture is strongly collectivist, to the point where talking about yourself is seen as prideful and individual work without the involvement of the family is at best uncomfortable and at worst inconceivable.

In the NPR piece, Cates gives some fascinating insights into his take on Amish psychology and discusses the innovative approach he needs when working with the culture.

It’s one of the most interesting and surprising radio pieces I’ve heard in a while, and is by the excellent Alix Spiegel, who also produced the gripping 81 words.

Link to NPR ‘One Man Tackles Psychotherapy For The Amish’.

Dan Ariely on the psychology of cheating

Behavioural economist Dan Ariely gives a fantastic 15 minute TED lecture on the psychology of cheating that explores numerous fascinating and counter-intuitive influences on how we bend the truth for personal benefit.

Ariely discusses some curious social influences, including the fact that seeing someone else cheat may actually decrease the general cheating of the group, but only if they perceive they are part of a different or rival group. Seeing someone cheat who is part of your ‘in-group’ seems to reliably increase dishonesty.

He also notes various effects of changing the form of the benefit. Simply making the reward tokens that can be exchanged for money, rather than just directly paying, greatly increases cheating, even though the value is identical in both cases.

Ariel does some fascinating research and is the author of Predictably Irrational, an excellent book which I thoroughly recommend.

The talk is similarly enjoyable and Ariely makes links between his own studies on cheating and the current financial meltdown.

Link to Dan Ariely’s TED talk.

Sweet anaesthesia and the mystery of consciousness

Discover Magazine has an excellent article on the science of anaesthesia and why doctors need to struggle with the problem of consciousness to make someone comfortably numb.

If you’re not familiar some of the mysteries of anaesthesia, you may be surprised to know that we don’t actually know how most anaesthetics work and we have no reliable way of telling whether someone is unconscious.

This is important because general anaesthesia usually involves two types of drug, muscle relaxants and hypnotics. It’s possible that the muscle relaxants have their paralysing effect but the hypnotics don’t fully work, so you’re awake and aware, but don’t respond when you’re touched or talked to.

Hence anaesthetists would love a device which says whether someone is concious or not, but unfortunately, divining consciousness from the brain is one of the hardest problems in science. So, they’ve come up with various other methods:

Sometimes the anesthesiologist will use a blood pressure cuff on a patient’s arm to block the muscle relaxants in the bloodstream. Then the doctor asks the patient to squeeze a hand.

This sort of test can distinguish between a patient who is awake and one who is out cold. But at the borderline of consciousness, it is not very precise. The inability to raise your hand, for example, doesn’t necessarily mean that you are unconscious. Even a light dose of anesthesia can interfere with your capacity to keep new pieces of information in your brain, so you may not respond to a command because you immediately forgot what you were going to do. On the other hand, squeezing an anesthesiologist’s hand may not mean you’re wide awake. Some patients who can squeeze a hand will later have no memory of being aware.

Seeking a more reliable measuring stick, some researchers have started measuring brain waves. When you are awake, your brain produces fast, small waves of electrical activity. When you are under total anesthesia, your brain waves become deep and slow. If you get enough of certain anesthetics, your brain waves eventually go flat. Most anesthesiologists monitor their patients using a machine known as a bispectral index monitor, which reads brain waves from electrodes on a patient’s scalp and produces a score from 100 to 0. But these machines aren’t precise either. Sometimes patients who register as unconscious can still squeeze a hand on command.

The article then goes on to discuss some fascinating neuroscience studies that use anaesthesia to try and understand what changes in the brain as someone slips into unconsciousness.

It’s a great read and an interesting look into what you might called ‘applied consciousness research’.

Link to ‘Could a Dose of Ether Contain the Secret to Consciousness?’

Dominant chemicals

Photo by Flickr user Ed Yourdon. Click for sourceAnthropologist Helen Fisher has done some fascinating work on the neuroscience of love and romantic relationships, but she hooked up with the dating site Match.com a few years back and seems to have lost the plot a bit, or at the very least, is being taken for a ride by their PR department.

Match.com’s press releases regularly get in the news as ‘science’ stories and the latest ones are doozies. You could not think of a more prefect storm of celebrity gossip, relationships, and junk science.

People have one of four chemicals in their brain that moulds romantic chemistry, scientists explain.

In ‘builders’ like Aniston, serotonin is the dominant chemical, making them calm and cautious.

‘Explorers’, like Brad Pitt, meanwhile, are led by dopamine, creating a more spontaneous and risk-taking romancer.

And, yes, you’ve guessed it, Brad’s current partner Angelina Jolie is an ‘explorer’, too.

Professor Helen Fisher, an expert in the science of love, said: ‘It’s possible to scientifically understand why people partner better with certain types.’

Possible, but presumably, unprofitable.

Actually, there has been some work correlating relationship or attachment style to the genetics of neurotransmitter receptors.

However, the concept of a ‘dominant chemical’ makes no sense at all and Fisher’s categories have been made up by her and are not used by anyone else.

Saying that, my dominant chemical is caffeine. Which makes my ideal partner… an energy drink?

Link to study summary on relationship style and genetics.
Link to study summary on attachment style and genetics.

(Thanks Petra!)

Wiring and plumbing in the brain

Frontiers in Human Neuroscience has a great two page article that nicely summarises the thinking about how blood flow measured by brain scans relates to the workings of the neurons.

No one with common sense would believe that in a house, water movements in pipes could tell you how many lamps are on and how much fuel is used for heating. Surprisingly most neuroscientists are convinced that in the brain monitoring local cerebral blood flow (CBF) what I call plumbing, is a reliable surrogate method to localize electrical neuronal activity and monitor metabolic events.

The piece is by neuroscientist Jean Rossier, and he discusses the two main theories of how blood flow relates to what the neurons are doing.

The ‘metabolic hypothesis’ assumes there is a causal link between how much energy the neurons need, in the form of glucose, and the subsequent regulation of blood flow in the brain. In other words, the neurons signal the need for energy, which is delivered later.

The ‘neurogenic hypothesis’ hypothesis, suggest that blood flow can be ‘pre-ordered’, in anticipation of neural activity.

Needless to say, it’s important to understand the exact relation between the operation of the neurons and blood flow, because brain scanning studies typically measure blood flow to infer the working of neurons and hence the relationship to cognitive or mental processing.

The Frontiers in Human Neuroscience article is a concise piece which discuss the neuroscience of this link, and covers some of the most recent studies which have attempted to make sense of what brain scans tell us when we’re doing psychology experiments.

Link to article ‘Wiring and plumbing in the brain’.
Link to PubMed entry for same.

Freud association

So what is it with all the Freud impersonators on Twitter? I’ve found six so far:

Sigmund Freud. Austrian psychiatrist.

Sigmund Freud. I am the father of psychoanalysis.

sigmund freud.

Sigmund Freud. How does that make you feel?

sigmund_freud. [In French].

sigmund. [In Russian].

If you’d rather another style of analysis, there are also Jacques Lacan and Carl Jung impersonators.

Everyone else is using it to free associate and they’re using it for wish fulfilment. What gives?

The PTSD Trap

Scientific American has a knock-out article that questions whether the diagnosis of post-traumatic stress disorder is a coherent psychological concept or whether it is actually making the situation worse for soldiers with post-combat mental health problems.

As we’ve noted before, PTSD is a controversial diagnosis for two major reasons. The first is that it is not clear that the diagnosis describes anything different from other forms of anxiety and depression, except for that fact that it is related to a specific traumatic incident.

The second is that the diagnosis was largely introduced after pressure from veterans’ lobbying groups after the Vietnam war. In fact, PTSD was originally called ‘post-Vietnam syndrome’ and there are concerns that while it was politically expedient at the time, the concept doesn’t lead to good mental health care.

In fact, combat stress reactions have taken various forms through the years of which PTSD is the latest reincarnation.

The SciAm article tackles research in the US military suggesting that the syndrome is over-diagnosed and that the treatment plan is counter-productive and actually encourages people to remain disabled.

But one of the most interesting things about the article is that it tackles the one of the core features of the diagnosis – that the anxiety symptoms are directly tied to a specific traumatic event.

Many people who are diagnosed with PTSD turn out not to have been traumatised by the event they later attribute the trauma to, or may not have even been traumatised at all.

J. Alexander Bodkin, a psychiatrist at Harvard’s McLean Hospital, screened 90 clinically depressed patients separately for PTSD symptoms and for trauma, then compared the results. First he and a colleague used a standardized screening interview to assess symptoms. Then two other PTSD diagnosticians, ignorant of the symptom reports, used another standard interview to see which patients had ever experienced trauma fitting DSM-IV criteria.

If PTSD arose from trauma, the patients with PTSD symptoms should have histories of trauma, and those with trauma should show more PTSD. It was not so. Although the symptom screens rated 70 of the 90 patients positive for PTSD, the trauma screens found only 54 who had suffered trauma: the diagnosed PTSD “cases” outnumbered those who had experienced traumatic events. Things got worse when Bodkin compared the diagnoses one on one. If PTSD required trauma, then the 54 trauma-exposed patients should account for most of the 70 PTSD-positive patients. But the PTSD-symptomatic patients were equally distributed among the trauma-positive and the trauma-negative groups. The PTSD rate had zero relation to the trauma rate. It was, Bodkin observed, “a scientifically unacceptable situation.”

This does not necessarily mean the people are lying, but may simply be attributing true symptoms to an unlikely source.

It’s a wonderfully thought-provoking article that’s sure to ruffle a few feathers.

The writer, David Dobbs, has also put a load of background material and links to the relevant studies on his blog, so you can get a more in-depth perspective if it sparks your interest in the area.

Link to article ‘Soldiers’ Stress: What Doctors Get Wrong about PTSD’.
Link to David Dobb’s background material for the article.

Cigarette smoking lady cops to read minds

The International Herald Tribune has an unintentionally funny opinion piece where a rather poorly informed journalist publicly wets his pants about ‘thought-decoding brain-scan technology’ which, apparently, the police could be carrying in the future so they’ll know if you’re thinking rude things about them.

When the police stopped me for running a red light recently, I was thinking “Don’t you cops have anything better to do?” But the words that came out of my mouth were a lot more guarded, something like, “Sorry, I thought it was green.” Sometimes it’s good to play the dumb foreigner.

The policewoman, a tough lady smoking a cigarette, glared at me. Was she reading my mind? No, I guess not, because she only gave me a warning. But beware, in a few years she might actually carry a device that can do that.

Research is rapidly advancing to allow thought-decoding through brain-scan technology, and it scares me to death. I don’t want anyone else in my head, and certainly not the police.

It’s a masterpiece of superficial reading of the scientific evidence and interpreting it in the most unrealistic and panicky way possible.

Link to IHT piece ‘Watch what you think’.

JAMA editors pressure antidepressant whistle blower

This is both odd and slightly disturbing. The Wall Street Journal reports that a medical researcher has been publicly insulted and allegedly threatened by the editors of the medical heavyweight Journal of the American Medical Association for calling out an antidepressant study for undisclosed conflicts of interest.

Jonathan Leo, a professor of neuroanatomy at Lincoln Memorial University, wrote a succinct and reasonably worded letter to the British Medical Journal noting that a study on the use of the antidepressant escitalopram (Lexapro) in stroke had concluded that the drug was better than other treatments, when in fact the data supported no such claims.

He also noted that the authors had failed to disclose their ties to the drug makers Forest Laboratories.

For his trouble he was phoned by the JAMA editors who allegedly made some academic threats to him, his students, and his superiors.

The story was followed-up by the Wall Street Journal who contacted the editor-in-chief Catherine DeAngelis. Surprisingly, DeAngelis publicly insulted Leo and is quoted by the WSJ saying:

“This guy is a nobody and a nothing” she said of Leo. “He is trying to make a name for himself. Please call me about something important.” She added that Leo “should be spending time with his students instead of doing this.”

When asked if she called his superiors and what she said to them, DeAngelis said “it is none of your business.” She added that she did not threaten Leo or anyone at the school.

This would perhaps be less shocking had the authors of the study in question not publicly apologised for omitting conflicts of interest and confirmed that the drug was not a superior treatment in subsequent letters to JAMA.

Ironically, DeAngelis has a reputation for closely monitoring conflicts of interest and has made JAMA a leader in requiring such admissions from authors.

Furious Seasons has been keeping tabs on the situation and as usual had the scoop before the WSJ got involved.

Link to WSJ piece “JAMA Editor Calls Critic a ‚ÄòNobody and a Nothing‚Äô”.

Is psychiatry a religion?

Photo by Flickr user Jillian Anne Photography. Click for sourceThe Journal of the Royal Society of Medicine just published a recent, and, presumably, slightly tongue in cheek article, drawing parallels between psychiatry, clinical psychology and traditional religious practices.

In reality, it’s not really attempting to address the question of whether psychiatry is a form of religion. Instead, it’s really asking whether psychiatry is now fulfilling some of the social roles that, for many people, were previously occupied by religion.

These include parallels between confession and therapy, proselytization and mental health campaigns, religious hierarchy and medical authority, sacraments and medication, and holy texts and diagnostic manuals.

The ‘psychiatry is a religion’ argument is weak, however, as despite similarities in some functions, none of these are core features of religion. As identified by cognitive anthropologist Pascal Boyer, the single common feature of all religious is a preoccupation with unseen sentient beings, of which psychiatry says nothing.

In fact, mainstream psychiatry remains firmly materialist – usually re-explaining experiences that many people attribute to spirits, forces or unseen influences as biological dysfunction. So, in the most fundamental sense, the practice of psychiatry is typically contra-religious.

You could argue that this is ‘replacing’ religion through colonising the spiritual sphere of explanation, but this makes it no more a religion than physics or evolutionary biology.

However, the article is interesting as it reflects an almost extinct genre in mainstream medical debate – a Thomas Szasz style view of psychiatry as a medical intrusion into an essentially social phenomenon. Namely, the classification and regulation of deviance, and the easing of distress caused by social maladjustment and existential crises.

The piece is probably better read as a concern about how medical theories have become the standard explanation for problems of human living, to the point where we assume that psychiatry can be an organising force in society.

Link to article ‘Is psychiatry a religion?’
Link to PubMed entry for same.

2009-03-13 Spike activity

Quick links from the past week in mind and brain news:

The Psychologist has a free bonus edition that collects some of its most popular articles.

A newly released report from the UN argues we should legalise illicit drugs to tackle organised crime.

The New York Times reports ‘Religious Thoughts and Feelings Not Limited to One Part of Brain’. No shit Sherlock.

The battle for Broca’s Area is expertly covered by Talking Brains.

Neurophilosophy has an excellent piece on the neuroscience of motivated forgetting, related to Freud’s theory of repression.

How could MDMA (ecstasy) help anxiety disorders? A neurobiological rationale. A highly speculative but interesting article from The Journal of Psychopharmacology.

The LA Times has a luke-warm article on our sense of time.

Prescribing hormone patches for women with ‘female sexual dysfunction‘ is put under the spotlight by Dr Petra.

The New York Times has an excellent piece on happiness research, or more accurately “a specific type of emotional and behavioral prediction”.

Early intellectual gap found for kids of <a href="http://sciencenews.org/view/generic/id/41529/title/Early_intellectual_gap_found_for_kids_of_older_fathers
“>older fathers aged 50 and over at conception, reports Science News.

Science Daily on a study finding that immigrants earn more money if they change their name from an obviously foreign one.

Mental illness doesn’t predict violence, finds biggest study to published in the Archives of General Psychiatry.

New Scientist has a Q&A on a ‘mass hysteria‘ outbreak in Nicaragua.

A priest jailed for child sexual abuse on the basis of ‘recovered memories‘ is having his case reviewed, reports The Nation.

Neurocase reports a case of a man who can speak without Broca’s area after tumor surgery.

A fantastic article on endangered languages with audio samples is available from Seed Magazine.

Seed Magazine also has a fantastic article on art and synaesthesia.

The official journal of the The International Neuropsychiatric Association is open-acess. Kudos to them!

New Scientist has an interview with psychiatrist Simon Wessely on mind-body interactions in illness.

Is Fraud Contagious? asks Newsweek with a look at a recent Dan Ariely study.

SciAm Mind Matters blog has an article on a neat study finding that actions, <a href="Metaphors of cleanliness
http://www.sciam.com/article.cfm?id=embodied-metaphor-moral”>metaphors and moral judgements can influence each other.

I thoroughly recommend Neurophilosophy for the most sensible coverage on the ‘reading perceived position from hippocampal activation study’ – badly described in the media as ‘mind reading’.

SciAm’s Jesse Bering column has an excellent piece on terror management and mortality salience.

CIA Awkwardly Debriefs Obama On Creation Of Crack Cocaine. Conspiracy comedy from The Onion.

When I get that feeling, I have sexual sneezing

Photo by Flickr user Mussels. Click for sourceA few months ago, a surgeon and a psychiatrist wrote an article for the Journal of the Royal Society of Medicine on cases of sneezing triggered by sexual thoughts and orgasm. The subsequent media coverage meant that the authors were contacted by members of the public who experienced similarly unusual sneezing triggers.

The researchers have written a fascinating follow-up letter to the same journal of summarise the reaction they got from their article, and the new cases they’ve discovered.

We surmised that sneezing induced by sexual ideation or orgasm may be under-reported. Subsequent media coverage has lead to many more members of the public stating that they also have this condition. Reports have been on the JRSM website, on internet-based media fora or by unsolicited contact with the lead author. In total the number of people we found reporting sneezing induced by sexual ideation through these disparate methods is 146 (which includes seven doctors), with a further seven reporting sneezing induced by orgasm.

These triggers of sneezing appear to be mutually exclusive; people report either sneezing upon sexual ideation or sneezing upon orgasm. Of those reporting sneezing upon sexual ideation 112 (77%) were men, as were all seven of those reporting sneezing with orgasm, but the gender disproportion may represent sexual bias in the reporting rather than the prevalence of these conditions. Nevertheless, these figures do show that these conditions are not infrequent, and imply that perhaps thousands of people in the UK are affected; many stated that they had never discussed this phenomenon and were relieved to hear that they were not alone.

We also wish to report that two people contacted us to state that several members of their family sneeze on a full stomach; this now doubles the number of families in the medical literature reported to have this as a trigger of sneezing. Interestingly, two of the people who reported sneezing on sexual ideation also admitted to a family history. One lady reported that her brother had the same phenomenon. A man reported that both his brothers and his father also had this. This implies, as we suggested in our original article, that all the unusual triggers of sneezing – light, full stomach, sexual ideation or orgasm – may be inherited in an autosomal dominant manner.

That last sentence is interesting, because a confirmed autosomal dominant pattern of inheritance means that it is likely to be due to changes in a single gene.

This doesn’t mean a single gene has evolved to trigger or prevent sneezing when people have sexual thoughts – this would likely be a ‘side-effect’ some other useful function.

Interestingly, sneezing in response to sunlight is known to be inherited in an autosomal dominant pattern.

Consequently, it has been given the name Autosomal dominant Compelling Helio-Ophthalmic Outburst syndrome, or the ACHOO syndrome.

Link to PubMed entry for original article.
Link to follow-up letter.

Projected at high speed for an unknown reason

I like this sentence in the summary from a recent paper on an unusual penetrating head injury:

We present a unique instance of a severe, high-energy, penetrating orbitocranial injury caused by a solid metallic rod that corresponded to the spray valve lever handle of a kitchen sink pre-rinse spray tap, which was fractured and projected at high speed for an unknown reason.

Link to PubMed entry for article.

Seven tactile illusions

New Scientist has got a nice feature online where they explain seven touch illusions you can try yourself, with the explanations for how they’re tricking your brain.

My favourite is probably the most simple, the ‘Aristotle illusion’:

One of the oldest tactile illusions is the Aristotle illusion. It is easy to perform. Cross your fingers, then touch a small spherical object such as a dried pea, and it feels like you are touching two peas. This also works if you touch your nose.

This is an example of what is called “perceptual disjunction”. It arises because your brain has failed to take into account that you have crossed your fingers. Because the pea (or nose) touches the outside of both fingers at the same time – something that rarely happens – your brain interprets it as two separate objects.

It’s a fantastic little collection and it follows on from NewSci’s recent collection of five auditory you can check out online.

Link to NewSci seven tactile illusions.

Far from the madding crowd

Photo by Flickr user aeminphilly. Click for sourceThe Economist has an excellent piece on crowd psychology and why group behaviour is essential in calming down street confrontations before they turn violent.

Crowds are often associated with senseless aggression, and perhaps the most widely quoted, and most colourful example, is from Gustave Le Bon’s 1895 book The Crowd.

He wrote that crowds showed several special characteristics such as “impulsiveness, irritability, incapacity to reason, the absence of judgment and of the critical spirit, the exaggeration of the sentiments, and others besides – which are almost always observed in beings belonging to inferior forms of evolution – in women, savages, and children, for instance”.

You can imagine how he went down at parties.

Nevertheless, this association between crowds and violence has remained a research focus for many years. Concepts such as deindividuation – a reduction in the feeling of personal identity and responsibility – are invoked to explain why ‘bad things’ supposedly happen when people congregate in groups. This also typically includes explaining why ‘bad things’ are allowed to happen without people intervening – the so-called bystander effect

The Economist article is interesting because it looks at research which seems to turn these assumptions on their head.

It discusses the work of psychologist Mark Levine, who studies crowd behaviour and has found that crowds actually act to reduce violence in many situations.

He has been analysing CCTV footage of incidents that control room operators thought might turn violent, not all of which did.

His first observation was that bystanders frequently intervene in incipient fights. The number of escalating gestures did not rise significantly as the size of the group increased, contrary to what the bystander effect would predict. Instead, it was the number of de-escalating gestures that grew. A bigger crowd, in other words, was more likely to suppress a fight.

Some incidents did end in violence, of course. To try to work out why, Dr Levine and his colleagues constructed probability trees to help them calculate the likelihood that a violent incident such as a punch being thrown would occur with each successive intervention by a bystander. Using these trees, they were generally able to identify a flashpoint at which the crowd determined which way the fight would go.

Judging the fight to begin with the aggressor’s first pointing gesture towards his target, the researchers found that the first intervention usually involved a bystander trying to calm the protagonist down. Next, another would advise the target not to respond. If a third intervention reinforced crowd solidarity, sending the same peaceful message, then a violent outcome became unlikely. But if it did not—if the third bystander vocally took sides, say—then violence was much more likely.

It’s a really eye-opening piece that’s well worth reading in full as it overturns both some common popular assumptions and some well-worn psychological clich√©s.

Link to Economist on ‘The kindness of crowds’.