Pioneers of psychology, in their own words

The Wellcome History of Medicine Centre has interviewed some of the UK’s cognitive science elders about the early days of neuropsychology and psychiatry research and have put all the video clips online.

The interviews are a wonderful insight into the earliest days of cognitive science research which are only hampered by their annoying presentation, so I’ve created YouTube playlists so you can just sit down and just watch each of the interviews from end-to-end.

Here they are:

Elizabeth Warrington was one of the pioneers of clinical and cognitive neuropsychology in the 60s and 70s and defined much of the field as we know it today. She was working at a time when it was rare for women to be working in medical research, let alone neuroscience.

Michael Rutter was one of the founders of child psychiatry and had a huge influence on the development of psychiatric epidemiology.

Richard Gregory is a highly influential cognitive psychologist who is famous for his work on visual perception and top-down (meaning-induced) influences on what we perceive.

Uta Frith is one of the world’s foremost autism researchers and has been involved in child neuropsychology research since the 1960s.

All of the interviewees have been working for over 50 years, have been founders of their field, and are still involved in research.

Elizabeth Warrington is a personal hero of mine. She not only made some of the foundational discoveries in neuropsychology, but also was one of the creators of many of the assessment methods and techniques we use both for assessing the extent of brain injury and the understanding of what brain damage can tell us about normal brain function.

Actually, I have the minor honour of being Elizabeth Warrington’s neuropsychological ‘grand child’, as I learnt a huge amount working with neuropsychologist Pat McKenna (another one of my personal heroes), who was one of the first people who was trained by Warrington.

A minor connection but one I am proud of, and I’m sure you can see why when you hear her discuss her work in the interview.

The other interviews are also thoroughly engrossing and are like being told stories of times past by people with wisdom of experience behind them.

Buck Rogers is not a blueprint

A quote from a recent Wired article that discusses a project to create a computer architecture based on the neurobiology of the brain. It sounds suspiciously like it’s based on Dr Theopolis from 70s TV series Buck Rogers in the 25th Century:

In what could be one of the most ambitious computing projects ever, neuroscientists, computer engineers and psychologists are coming together in a bid to create an entirely new computing architecture that can simulate the brain’s abilities for perception, interaction and cognition. All that, while being small enough to fit into a lunch box and consuming extremely small amounts of power.

Just because you didn’t mention Buck Rogers in the grant application, it doesn’t mean we don’t know what you’re up to.

I mean, I’d love to recreate the magic of ‘Planet of the Amazon Women’ too, but you’ll need more than a fully conscious cognitively aware AI than runs off two AA batteries.

If you’re completely mystified, and / or under the age of 30, you may want to check out this clip on YouTube. Dr Theopolis is the, er, lunch box like-AI on the table. He usually hangs round the neck of the annoying android Twiki.

On a slightly more serious note, I just checked out Kwabena Boahen’s Stanford talk where he discusses exactly this sort of project to create neurally inspired computer chips. Definitely worth a look.

Link to Wired article on cognitive computing.
Link to Kwabena Boahen’s talk on neurally inspired chips.

Formerly schizophrenia

The February edition of the British Journal of Psychiatry has a thought-provoking editorial by psychiatrist Jim van Os, arguing that we should reject the diagnosis of schizophrenia owing to its lack of validity and replace it with a concept of a ‘salience dysregulation syndrome’.

If you’re not familiar with the use of the term salience, it is used widely in cognitive science to describe the attention grabbing quality of things and psychosis is widely thought to involve, at least in part, a problem with the regulation of salience so normally unremarkable things seem important or alarming.

Although this idea has been kicked around for many years, it was popularised in recent years by an influential article by psychiatrist Shitij Kapur called ‘Psychosis as a state of aberrant salience’, as differences in dopamine function are regularly found in studies on delusions and hallucinations.

Importantly, disturbance in dopamine-regulated salience does not seem specific to schizophrenia, but is common across all psychotic disorders.

Consequently, van Os reviews the scientific literature that has repeatedly found that the diagnosis of schizophrenia does not seem to be a cut-and-dry category and that psychosis appears in various forms to differing degrees throughout the population.

He particularly argues for the importance of explicitly naming the problem as a ‘syndrome’, as despite that fact that most people accept that it is not a single disorder, it can get treated as such simply out of habit:

First, although criticisms about the diagnostic construct of schizophrenia may be deflected with the argument that it is merely a syndrome (the association of several clinically recognisable features that often occur together for which a specific disorder may or may not be identified as the underlying cause), the problem is that its very name and the way mental health professionals use and communicate about the term results in medical reification and validation through professional behaviour rather than scientific data, exposing psychiatry to ridicule and hampering scientific progress. It may be argued, therefore, that if it is a syndrome, calling it as such may serve to remind professionals (and downstream of these, the rest of the world) of the relatively agnostic state of science in this regard.

Second, given the fact that maximum utility in terms of conveying clinical information may be obtained by combining categorical with dimensional representations of psychopathology, DSM–V and ICD–11 may be best served by creating separate categorical and dimensional axes of the psychopathology of psychotic disorders.

Link to article ‘A salience dysregulation syndrome’.
Link to PubMed entry for same.

Music to my mind

I’ve just realised that a new series of ABC Radio National’s excellent All in the Mind just kicked off the other week with a fantastic programme on the therapeutic potential of music.

The programme is both wonderful to listen to because music is threaded woven throughout the interviews, but it’s also a critical and well-balanced look at music therapy.

It immediately tackles the fallacy of ‘Mozart makes you smarter’ but then goes on to discuss the evidence behind music therapy itself.

This form of treatment is usually regarded with a great deal of enthusiasm by staff and patients but doesn’t have a huge research base to back it up in comparison to other forms of psychological treatment, largely, it has to be said, because music therapists get very little in the way of research training.

However, the studies that have been done (for example, see this Cochrane review on its effect in schizophrenia) suggest it can be quite effective.

The programme is a really great introduction to the topic and great to see AITM back with a new series.

Link to AITM on ‘Music: Is it really therapeutic?’.

The light controlled brain and other tales

Stanford University have put a series of engaging TED style 10 minute lectures up on YouTube where some of their leading researchers discuss cutting-edge cognitive science research – curing blindness with neural implants, brain computer interfaces, neural pathway mapping, creating brain inspired computer hardware, visualising desire and controlling neurons with light.

Getting lab scientists to do short, engaging online lectures aimed at a bright and curious audience is a fantastic idea. These new Stanford talks have a high production quality and have obviously been prepared with a great deal of care as they are incredibly easy to watch.

I’ve not watched them all yet, but so far the talk on the neuroscience and stem cell treatment of blindness is a particular highlight.

In this presentation, psychologist Brian Wandell discusses the science of perception and the treatment, as well as the remarkable case of Mike May, the world-record holder for blind downhill skiing who volunteered to try the experimental treatment.

A fantastic series that’s well worth checking out.

Link to Stanford neuroscience TED-style talks.

Weaving a history of psychiatry from states of mind

BBC Radio 4 have just concluded a fantastic five part radio series called States of Mind on the history of psychiatry in the UK since the 1950s, covering the death of the asylum, to the age of Prozac, to visions of the future.

It’s produced and presented by the fantastic Claudia Hammond and weaves together historical research, commentary from researchers and the personal stories of patients and staff who have memories of treatment through the last 60 years.

Although it specifically focuses on the UK, in many ways it reflects the history of mental health in many parts of the world owing to the fact that Britain has tended to be a leader in both psychiatric treatment and radical views of mental health.

The five parts, all of which have the streamed audio available online, are:

Total Institution
Altered States
Community Care?
Happiness in a Pill?
Which Way Now?

I was altered to the series by the increasingly excellent Frontier Psychiatrist blog which is also well worth checking out.

Link to States of Mind page.

Encephalon 63 hits the jackpot

The 63rd edition of the Encephalon psychology and neuroscience writing carnival has just been published online and has the latest from the last fortnight’s mind and brain hot topics.

A couple of my favourites include Ouroboros on the link between pessimism and premature ageing, and an article on the commonly discussed relationship between phases of the moon and behaviour from PodBlack.

There’s much, much more where that came from, so hit the links to get the full monty.

Link to Encephalon 63.

If It’s Difficult to Pronounce, It Must Be Risky

I’ve just found a short-but-sweet study recently published in Psychological Science that shows that we tend to rate things with difficult to pronounce names as more risky than those with names that we can say more fluently.

Psychologists Hyunjin Song and Norbert Schwarz created names of notional food additives and asked the participants to rate how hazardous they seemed.

Easy to pronounce ‘additives’ with names like Magnalroxate were consistently rated as less risky than names such as Hnegripitrom.

Wanting to see whether the same effect held for risks that could be seen as exciting, they ran a similar experiment but where participants were asked to rate amusement park rides.

Rides with names like Ohanzee were rated as less likely to make you sick than difficult-to-pronounce rides with names like Tsiischili, but were also rated as less adventurous.

The researchers note that their study is in line with previous research on cognitive biases, which has found that we tend to underestimate the risk of familiar things and over-estimate the risk of things we don’t know so well.

Link to PubMed entry for study.

2009-02-06 Spike activity

Quick links from the past week in mind and brain news:

Furious Seasons has the curious news that FDA has linked anti-depressants to the development of neuroleptic malignant syndrome. Curious as NMS is traditionally linked to dopamine inhibitors, and serotonin syndrome has several similar symptoms but is already known.

Readers build vivid mental simulations of literary narratives, suggests brain scanning study.

Brain has a interesting commentary on the vascular theory of migraine – ‘a great story wrecked by the facts’.

The wonderful RadioLab has a brief post-season follow-up programme with an excellent section on ‘stereotype threat‘.

USA Today covers an fMRI study on a women with hypermnesia or ‘super memory’ as the paper calls it.

Speed dating as a method for studying the psychology of attraction is discussed by Science News.

Not Exactly Rocket Science covers research suggesting colours affect the mind – red improves attention to detail, blue boosts creativity.

Hypothesis / conclusion confusion hits BBC News, again, as it says Alzheimer’s ‘is brain diabetes’.

Neurophilosophy has a typically excellent article on a study looking at how the age of a memory being recalled is linked to which brain areas are active during remembering.

A study on the epidemiology and prognosis of coma in soap operas is covered by Neurotopia.

Time magazine asks will plastic surgery make you happier? Unlikely, is the answer.

Financial bubbles, economic crashes and cognitive biases are discussed by The Atlantic.

Nth Position reviews an interesting looking new book on the ‘globalisation of addiction‘.

A study on the negative effects of violent video games on social helping is discussed by New Scientist.

BoingBoing notes news that a Hollywood film about amnesic patient H.M. could be in the pipeline.

Activities performed in unison, such as marching or dancing, increase loyalty to the group, according to a new study covered by New Scientist.

BPS Research Digest asks how much thought do we put into our moral judgements?

There’s only so much science can tell us about human morality, argues Howard Gardner in an article for Slate.

Cognitive Daily has a great piece on how the Kanizsa illusion is being used to study how we recognise shapes.

Never mind the quality, look at the width

Image by Flickr user Scott Robinson. Click for SourceThe New York Times has a fascinating snippet on how cooperation with others to get a monetary reward is not influenced by the value of the reward, but by the numbers that describe it.

In the study, when the reward was described as rising from 3 cents to 300 cents cooperation increased – but when it was described as rising from 3 cents to 3 dollars, it had no effect.

The experiment was carried by psychologists Ellen Furlong and John Opfer who were interested in comparing how our reasoning is affected by the representation of value.

The researchers asked volunteers to take part in a behavioral test known as the prisoner’s dilemma, in which two partners are offered various rewards to either work together or defect.

The idea is that in the long term, the participants earn the most money by cooperating. But in any given round of play, they make the most if they decide to turn against their partner while he stays loyal. (The reward is lowest when both partners defect.)

When the reward for cooperation was increased to 300 cents from 3 cents, the researchers found, the level of cooperation went up. But when the reward went from 3 cents to $3, it did not.

We covered a study late last year that also found a similar effect: people were swayed more by higher numbers in adverts even when the alternative described exactly the same thing but using smaller units.

Link to short NYT piece ‘$1? No Thanks. 100 Cents? You Bet’.
Link to academic article on study.
Link to DOI entry for same.

Looking into the mind of God

This week’s New Scientist has an interesting article summarising the current thinking on the psychology of religion.

The research treats religion and belief in God or other supernatural entities as a natural consequence of how the brain works.

This has taken two main strands in the research literature: the first is that these tendencies to believe in supernatural forces have evolutionary benefits for social cohesion and kinship, which is why they have been selected for.

The other is that these beliefs are a side-effect of the actions of other useful cognitive processes we have developed. In other words, we have certain mental abilities, typically attributing intention and desire, which we unwittingly over-apply and hence attribute random uncontrollable events to mysterious but intelligent beings.

The article is not particularly in-depth but is notable for its breadth of coverage and will give you a taste for the direction in which the cognitive science of religion is heading.

Link to NewSci article ‘How your brain creates God’.

NeuroPod on pheromones, neural nets, fMRI and sleep

The latest Nature Neuropod neuroscience podcast has just hit the net, with a great selection of discussions and interviews covering everything from pheromones and sexual attraction to the impact of poor quality sleep on memory.

This final section on an intriguing and recently published study found that even mild disturbance that didn’t wake the sleeper but knocked them out of deeper sleeper into the shallower sleep stages could still disrupt the retention of material learned the previous day.

However, as I am remarkably tired myself I need as much deep sleep as I can get, so I shall leave the rest of the podcast as a voyage of discovery. Enjoy!

Link to Neuropod home page with audio.
mp3 of latest podcast.

The hashish inspired art of Jean-Martin Charcot

While searching for material on the famous 19th Century French neurologist Jean-Martin Charcot, I noticed that a number of online art shops sell drawings he did, apparently while under the influence of hashish – so I’ve been trying to find out more.

charcot_hashish.jpg

The strip above is only part of the image, as despite the fact that it is now in the public domain, most of the online sources deliberately obscure it, presumably in an attempt to get you to buy their posters while pissing off potential customers at the same time.

However, it seems that the picture is likely to be genuine. This is from a book on Charcot’s life where a contemporary recounts their hashish smoking escapades:

As soon as he was under the influence of the narcotic, a tumult of phantasmogoric visions flashed across his mind. The entire page was covered with drawings: prodigious dragons, grimacing monsters, incoherent personages who were superimposed on each other and who were intertwined and twisted in a fabulous whirlpool bringing to mind the apocalyptic visions of Van Bosh and Jacques Callot.

A 2004 article in the medical journal European Neurology discussed his lifelong interest in art and drawing, and contains a sketch of a scene from Hell also apparently created while stoned.

If anyone does know of a high quality online source of these drawings online, do let me know, as I’d particularly love to see the larger image in its full glorious detail.

Link to European Neurology on ‘Charcot and Art: From a Hobby to Science’.
Link to PubMed entry for same.

Like tears in the rain

The New York Times has a great short article on the science of crying, covering recent studies that have investigated the common idea that it is a useful way of releasing pent-up emotion.

The idea that crying is cathartic has been researched more than I realised with numerous large scale studies tackling in what situations people cry, as well what impact it has on our emotional state.

Now, some researchers say that the common psychological wisdom about crying ‚Äî crying as a healthy catharsis ‚Äî is incomplete and misleading. Having a ‚Äúgood cry‚Äù can and usually does allow people to recover some mental balance after a loss. But not always and not for everyone, argues a review article in the current issue of the journal Current Directions in Psychological Science. Placing such high expectation on a tearful breakdown most likely sets some people up for emotional confusion afterward…

In a study published in the December issue of The Journal of Social and Clinical Psychology, Dr. Rottenberg, along with Lauren M. Bylsma of the University of South Florida and Ad Vingerhoets of Tilburg University in the Netherlands, asked 5,096 people in 35 countries to detail the circumstances of their most recent crying episode. About 70 percent said that others’ reactions to their breakdown were positive, comforting. But about 16 percent cited nasty or angry reactions that, no surprise, generally made them feel worse.

The science of crying was also covered in a recent BPS Research Digest post that discussed another one of Rottenberg’s studies that focused entirely on females.

Link to NYT piece ‘The Muddled Tracks of All Those Tears’.

Hello, my name is Trouble

Time magazine has an interesting article on links between given names and behaviour, with a new study finding children with unpopular names are more likely to be get in trouble with the law.

This doesn’t mean that being called an unusual name causes criminality – the article notes that boys with unpopular names are likelier to live in single-parent households and be poorer, which are also known to be linked to higher levels of offending.

However, it does add to a growing body of research suggests that our names have a curious influence on our life.

A great review article in The Psychologist from last year covered much of findings, including the fact that people tend to buy products they share initials with, those whose names start with C or D are more likely to receive those grades than are other students, and people called Louis are more likely to live in St. Louis, Mary in Marysville and so on.

The same effect also seems to happen with initials, so Marys are also more likely to live in Manchester.

However, the Time article focuses more on how your name affects how others react towards you and perceive you, which may have a reciprocal impact on your own life chances:

The short answer is that our names play an important role in shaping the way we see ourselves — and, more important, how others see us. Abundant academic literature proves these points. A 1993 paper found that most people perceive those with unconventionally spelled names (Patric, Geoffrey) as less likely to be moral, warm and successful.

A 2001 paper found that we have a tendency to judge boys’ trustworthiness and masculinity from their names. (As a guy whose middle name is Ashley, I can attest to the second part.) In a 2007 paper (here’s a PDF), University of Florida economist David Figlio found that boys with names commonly given to girls are likelier to be suspended from school.

And an influential 1998 paper co-authored by psychologist Melvin (a challenging first name if there ever was one) Manis of the University of Michigan reported that “having an unusual name leads to unfavorable reactions in others, which then leads to unfavorable evaluations of the self.”

Link to Time on the effects of names.

If Freud were a woman

I’ve just found this clever short essay that parodies Freud by imagining that he was a woman.

It discusses the work of Phyllis Freud, rather than the better known Sigmund, who puts a female perspective in the centre of his male-centric theories.

As Phyllis observed…there was ‚Äúyet another surprising effect of womb envy, or the discovery of the inferiority of the penis to the clitoris, which is undoubtedly the most important of all…that masturbation…is a feminine activity and that the elimination of penile sensuality is a necessary pre-condition for the development of masculinity.‚Äù

In this way, Phyllis Freud wisely screened all she heard from her testyrical patients through her understanding, still well accepted to this day, the men are sexually passive, just as they tend to be intellectually and ethically. After all, the libido is intrinsically feminine, or, as she put it with her genius for laywoman’s terms, “man is possessed of a weaker sexual instinct.”

This was also proved by man’s mono-orgasmic nature.

Apparently it’s taken from one of the many, many feminist critiques of Freud’s work, who famously focused on theories of male psychology because women just seemed too baffling.

Link to ‘What if Freud were Phyllis?’