Reframing mental illness

mental_health_page.jpgA recently concluded confererence at London’s Institute of Psychiatry has been debating the classification and boundaries of mental illness and has been challenging the traditional views of psychiatric medicine.

There have been longstanding critics of psychiatry, notably people like R.D. Laing and Thomas Szasz, who have argued that the medical concepts of mental illness are flawed, or that they are used to unjustly silence society’s outsiders.

More recently, psychiatric classification, and particularly the separation of mental disorder into diagnoses such as ‘schizophrenia‘ and ‘bipolar disorder‘ have been challenged by mainstream psychiatrists on the basis of scientific discoveries.

For example, an editorial in May’s British Journal of Psychiatry argued that that schizophrenia and bipolar disorder are on a continuum, based on genetic evidence that is increasingly showing that similar genes are found in people who receive either diagnosis.

Other criticisms, echoed at the recent London conference, have been based on the coherence of psychiatric definitions and how well they reflect the diverse experiences of people who live through mental distress.

The conference discussed how understanding the first-person conscious experience of mental illness (as opposed to, or in combination with, scientific measures) can make for a more accurate understanding, and hopefully, treatments for those in need.

This approach is known as phenomenology and was championed by a number of continental philosophers who argued that science will only ever give a partial explanation because objective measures always leave something of the ‘lived experience’ missing.

One increasingly popular view of psychosis, the reality-bending mental state that can involve hallucinations and delusions, suggests that it is not an all or nothing state as psychiatric diagnosis suggests, but a range of experiences that are distributed throughout the population.

Recent studies have typically reported that about 10-11% of the general population score about the average of psychotic patients in psychiatric wards, on measures of unusual thinking or perceptual distortion, despite not needing psychiatric help or becoming significantly distressed or disabled.

Link to details of the recent conference on ‘Phenomenology and Psychiatry for the 21st Century’.
Link to BBC News on the conference and the boundaries of madness.

The robots are coming

sexyrobot.jpgThe Turing Test is where a human judge engages in a natural language conversation with two other parties, one a human and the other a machine, if the judge cannot reliably tell which is which, then the machine has passed and is deemed intelligent. Sex, it seems, turns the Turing Test on its head.

Blogger Jason Striegel found out that someone had advertised his instant messager address as belonging to a dirty-talking software sex bot. Frustratingly, no-one believed him when he protested his humanity.

the people who contacted me fell into one of two camps: people who thought they were contacting a celebrity and people who thought they were contacting a robot. As I talked to more and more of these folks, I began to discover something really disturbing about myself:

I consistently fail to be perceived as human.

fratburger86: hey. so you’re a sex bot?
jmstriegel: umm, no. who the hell are you?
fratburger86: yeah you are! i found your im online
jmstriegel: that’s fine and all, but i’m pretty sure you have me confused with someone else.
fratburger86: just a normal chat bot then?
jmstriegel: nope. i’m human
fratburger86: ok. sure.

jmstriegel: seriously, i think you want to talk to someone else.
fratburger86: i knew it!!!
fratburger86: you are totally a robot!

In contrast, real-life sex bot software Jenny18 consistently fools chat-room users who seem oblivious to the fact that she is nothing more than a few hundred lines of code, hacked from the original simulated chat software ELIZA, designed to repeat set phrases and reflect simple sentences back to the user.

jenny18: u r getting me hot =)
GoldenBoy2222: Ride me
jenny18: mmm i want 2 ride you..
GoldenBoy2222: yeah… of course
jenny18: MMmmm.. yes!
GoldenBoy2222: What r ur measures?
jenny18: yep.
GoldenBoy2222: yeah… What r ur measures?
jenny18: yep.
GoldenBoy2222: Say… What r ur measures?
jenny18: i bet lol
GoldenBoy2222: yes? An what r ur measures?
jenny18: mm hmm?
GoldenBoy2222: Good…

The archives of chat sessions contain many more examples of humans exciting themselves at Jenny18’s dirty, nonsensical (and definitely not safe for work) sexy chatter.

Link to ‘How I failed the Turing test’.
Link to Jenny18 description and chat archives.

Noel Sharkey on robot intelligence

noel_sharkey.jpgABC Radio’s In Conversation has an interview with cognitive scientist and AI researcher Professor Noel Sharkey who discusses his life, his work and the creation of robot intelligence:

“Noel Sharkey left school at 15, became a singer and took substances. It was while reflecting on the effects of an acid trip (he had taken LSD) that he began wondering about the limits of the mind. Since then he has explored the nature of machine intelligence, experimented with robotic evolution and mused on what kind of thinking is beyond computers. Professor Sharkey, from the University of Sheffield, is here for National Science Week.”

Realaudio of interview.
Link to In Conversation website.

Tribute to neuropsychology pioneer David Marr

visual_swirl.jpgCognitive science site Mixing Memory has a tribute to David Marr, a pioneer in understanding visual perception, and in combining neurological and psychological levels of explanation, who died tragically early at the age of 35.

Marr wanted to understand how the brain could start with two-dimensional arrays of light spots on the retina and subsequently produce a rich three-dimensional visual experience.

He argued that the final visual experience is produced by a series of computations that extract important information, such as edges, object groupings and depth information, from basic visual data.

Crucially, he also gave the mathematical procedures, based on an understanding of the biology of the visual system, that might perform these operations.

As well as producing one of the most influential theories of vision, he also influenced how neuroscientists and psychologists think about how the brain works. He proposed that the biology of the brain serves to process information, and that brain cells can be modelled with accurate computational models.

Marr died of leukemia at the age of 35, and produced his most influential work (the book Vision) in the knowledge he had little time left to complete it.

It was published two years after his death in 1982 and is prefaced by the statement “This book is meant to be enjoyed”.

Link to article on Mixing Memory (including link to Marr’s work)
Link to biography of Marr.

2005-09-02 Spike activity

Quick links from the past week in mind and brain news:

spike.jpg

Brain areas associated with pleasure and anxiety are activated when assessing risk.

Early research suggests that emotion can increase the risk of an attack in people with asthma.

The first book on vetinary psychiatry is published.

Safety Smock‘ – especially designed clothes for preventing suicide (nicked from BoingBoing).

More on Edinburgh University’s Koestler Parapsychology Unit, this time from The Guardian.

Computer scientists devise algorithm to ‘learn’ languages unaided.

Circadiana discusses the interaction between sleep cycles and Bipolar disorder.

Iron Maiden’s d√©j√† vu

eddie-figure-somewhere-l.jpgWhilst looking for an article in the British Journal of Psychiatry I came across this curious letter, noting an accurate description of déjà vu in the lyrics of an Iron Maiden song.

Sir: Sno, Linszen and De Jonge have <a href="reviewed a number of descriptions of d√©j√† vu in poetry and literature (Journal, April 1992, 160, 511-518). There is another particularly striking example. It is the song “D√©j√† vu” by Dave Murray and Steve Harris (1986) from the album Somewhere in Time by the rock group Iron Maiden. It vividly illustrates many of the points made by Sno et al in their article. The song gives an accurate phenomenological description of d√©j√† vu. It implicitly suggests reincarnation as an explanation and it refers explicitly to precognition (“And you know what’s coming next”) and to feelings of depersonalisation (“And you feel that this moment in time is surreal”). The full lyrics are reproduced here with the kind permission of Iron Maiden Publishing (Overseas) Ltd, administered by Zomba Musica Publishers Ltd.

When you see familiar faces
But you can’t remember where they’re from
Could you be wrong?

When you’ve been particular places
That you know you’ve never seen before
Can you be sure?

‘Cause you know this has happened before
And you know that this moment in time is for real
And you know when you feel déjà vu.

Chorus:
Feels like I’ve been here before (rpt. four times)

Ever had a conversation
That you realise you’ve had before
Isn’t it strange?

Have you ever talked to someone
And you feel you know what’s coming next
It feel pre-arranged.

‘Cause you know that you’ve heard it before
And you feel that this moment in time is surreal
‘Cause you know when you feel d√©j√† vu

Chorus

Sno et al suggest that psychiatrists “should be encouraged to overstep the limits of psychiatric literature and read literary prose and poetry as well” because “novelists and poets excel in [the] ability to depict subjective experiences”. While agreeing with this point of view, I would go further. Literature and art are capable of an emotional response in the person who experiences them. This can lead to a far deeper empathic or subjective understanding of an experience than is possible from a scientific description. Wide reading and exposure to the arts enables us to share, if only partially and in completely, the experience of our patients. We can understand them better, not just at an intellectual level, but as people like ourselves.

Bill Plummer
Mental Health Advice Centre, Folkstone, Kent.

Rock on Dr Plummer. Even more intriguingly, the following letter in the same issue is about hypnotised lobsters, but I think that will have to wait until another time.

Link to letter’s PubMed entry.

Reduplicative paramnesia

Reduplicative paramnesia is the delusional belief that a place or location has been duplicated, existing in two or more places simultaneously, or that it has been ‘relocated’ to another site. It is one of the delusional misidentification syndromes and, although rare, is most commonly associated with acquired brain injury, particularly simultaneous damage to the right cerebral hemisphere and to both frontal lobes.

From a Wikipedia article on reduplicative paramnesia I’ve just created. Enjoy (and excuse the typos!).

Women’s psychology magazine to launch in UK

psychologies_fr_jan.jpgA new glossy women’s magazine is due to launch in the UK that covers philosophy and psychology, as well as celebrity interviews and lifestyle stories.

Psychologies already exists in France, where the French version (pictured on the right) sells over 300,000 copies a month. It is hoped that UK women will be similarly intrigued by stories that discuss “what we’re like, not just what we look like”.

A write-up in The Independent claims that the magazine will be “academically rigorous”, presumably basing advice and analysis on established research.

It is clear that the magazine is not straying too far from the tried-and-tested format of women’s glossies, however, as beauty advice and celebrity interviews (Meg Ryan will be issue one’s cover girl) will still feature strongly.

Link to story from The Independent ‘Psychologies magazine: Not just a pretty face’.
Link to website of French Psychologies

Fortean Times on Koestler Parapsychology Unit

ft_sept_2005.jpgSeptember’s edition of the Fortean Times has a lead article on Edinburgh University’s Koestler Parapsychology Unit and the state of parapsychology research today.

The research centre is supported by money left in the will of controversial author Arthur Koestler, who had a long-standing interest, and some personal experience, with paranormal phenomena.

In contrast to much of the frankly dodgy science that the area attracts, the Koestler Unit conducts well-controlled scientific studies into potential psi abilities.

The article notes some interesting findings. For example, there seems to be a statistically significant effect, albeit very small in magnitude, when the results of the scientific studies on psi abilities are collated.

It also includes some insights from current and ex-parapsychological researchers on the future of the field, and whether the findings reflect genuine psi, or perhaps just some uncontrolled ‘noise’ in experimental design.

The article is only available in the print edition at the moment, but the Fortean Times put their lead articles online after a month or two, so look out for it on their website for those without copies on your local newstands.

Link to Fortean Times website.
Link to Koestler Parapsychology Unit website.

On hair and leadership

For at least half a century Americans have shown a marked aversion to electing bald men to their nation’s highest office. Excluding Gerald Ford (1974-77) who was bald but not elected, the last bald president was Dwight D. Eisenhower (1953-61). Europeans have been more sympathetic to the bare-headed politico (Churchill, Papandreou, Simitis, Giscard d’Estaing, Mitterand, Chirac, Craxi, Mussolini), but even they have lagged behind the Soviets, who inexplicably installed, if not exactly elected, bald and hirsute leaders in strict alternation: Lenin (bald), Stalin (hairy), Khrushchev (bald), Brezhnev (hairy), Andropov (bald), Chernenko (hairy), Gorbachev (bald) – a tradition that has been maintained in the Russian Republic with Yeltsin (hairy) and Putin (comb-over).

From p281 of Mutants: On the Form, Varieties and Errors of the Human Body by Armand Marie Leroi.

Death to common sense

deepthought.jpgOnline science think-tank Edge has a discussion about the role of common sense theories in explaining physics and cognitive science.

Science writer John Horgan bemoanes the fact that scientific theories have become so complex and fantastical that common sense has gone out of the window.

He cites various examples in the physical and ‘mind sciences’ which, he claims, demonstrates that theories are becoming useless and untestable.

In reply, Horgan’s comments are met with a robust response, with psychologist Daniel Gilbert going as far as saying “such a silly trifle that it doesn’t dignify serious response”!

Link to ‘In Defense of Common Sense’.

2005-08-26 Spike activity

Quick links from the past week in mind and brain news:

spike.jpg

Manchester University initiates a survey on out-of-body experiences – which you can participate in here.

Workaholics are better in bed claims questionable recent study.

The placebo effect causes real-life opioids to flood the brain.

Change blindness is particularly associated with a small area of the parietal lobe, finds magnetic brain stimulation study (via BoingBoing).

In the UK, suicide is most likely to occur on Mondays, possibly due to a “sense of unease over starting something new”.

Men score consistently higher on IQ tests than women, claims controversial new study.

Is daydreaming linked to Alzheimer’s ?

buckner_study.jpgA recent brain scanning study has been widely reported as suggesting that Alzheimer’s disease is linked to the brain functions of daydreaming. The actual study is both complex and interesting, although not as clear cut as the headlines make out.

Th research project, led by neuroscientist Randy Buckner, conducted brain scans on 10 people with Alzheimer’s disease and 8 older people without, and also used data from previous studies on young people.

The newly conducted scans looked at how amyloid plaques, damaging accumulations of proteins linked to Alzheimer’s disease, were distributed across the brain. Further scans looked for other types of structural changes in the brain, such as shrinkage.

This distribution was matched with activity from the scans of young people. In contrast to the structural scans, these functional scans looked at how active the brain was.

Normally, functional scans involve participants being asked to do a particular task. In Buckner’s study, however, the activity was from participants who were just ‘resting’ and were not asked to do any specific mental activity – something the researchers called ‘default activity’.

The researchers noted that ‘default activity’ showed a similar pattern in the brain to the distribution of amyloid plaques in Alzheimer’s disease (shown in the image on the right), and have suggested there might be a link.

There are several unanswered questions though, which the researchers themselves acknowledge.

One is simply that ‘resting’ or ‘default’ brain activity is a mystery, no one is quite sure what the brain is doing in this state. ‘Daydreaming’ is just an everyday term that is used, because we assume that’s what we do when we’re not doing much.

In reality, the brain areas highlighted by the study are involved in a range of diverse of contrasting mental activities.

A further difficulty is that the correlation between ‘default activity’ and amyloid plaque distribution was found between two sets of people. More convincing would be if these distributions were found to correlate in the same people.

With these issues in mind, the final difficulty is with interpreting the results. The researchers suggest that mental activity in younger adults could be related to the later development of Alzheimer’s, but there is no clear understanding of how this happens.

My guess is that ‘daydreaming’ is unlikely to be a significant part of this explanation, although as the scientific paper only mentions it in passing, I suspect the researchers don’t think so either.

Link to press release from Washington University.
Link to Reuters story “Daydreaming activity linked to Alzheimer’s”
Link to summary of scientific paper by Buckner and colleagues.

Cultural cognition update

As an update to the last post, on cognitive differences between Eastern and Western societies, Richard Nisbett was on BBC All in the Mind last night to discuss his findings.

He talks about the experimental results just released, as well his wider studies which have resulted in his book The Geography of Thought: How Asians and Westerners Think Differently – And Why.

Link to All in the Mind webpage for Tuesday’s edition.
Realaudio of programme.

Chinese and Americans differ in visual analysis

asian_girl.jpgAn experiment conducted by psychologist Richard Nisbett suggests that Chinese and American people analyse scenes differently. The Americans focused on the main object in the picture, while the Chinese took a more holistic approach, and examined more of the visual context.

Traditionally, Western societies are characterised as ‘individualistic’ and Eastern societies as ‘collectivist’, suggesting that in countries like China and Japan, the focus is on society as a whole, rather than each person’s individual characteristics.

Some have suggested that this reflects the different philosophical traditions of these cultures, with the West tending to approach problems by analytically breaking them down into component parts, and the East looking at problems in their wider context.

Nisbett’s experiment suggests that this tendency may influence mental function even on the unconscious level, as his effect was found when participants were simply asked to view pictures, while their eye movements were tracked with an infra-red camera.

Importantly, the participants were unaware of the full intention of the experiment, and were told they were taking part in a study to test memory for pictures.

Why the picture of the Chinese girl? I just thought she looked beautiful.

Link to write-up from Science (with good example of eye-tracking result).
Link to New Scientist story.
Link to Scientific American story.

Cabinet on neural network pioneer Walter Pitts

walter_pitts.jpgAn article from art and culture magazine Cabinet discusses the prodigious and tragic life of neural network pioneer Walter Pitts, who was one of the major forces in the early development of computational models of the mind and brain.

Pitts started attending university lectures, uninvited, during his teenage years, and by the age of 17 was working with neurophysiologist Warren McCulloch. As Pitts was homeless and without an income at the time, McCulloch invited Pitts to live in the family home.

Together, they wrote one of the foundational papers in cognitive science, where they demonstrated that individual neurons, mathematically modelled, could be combined in networks to simulate logical computation. This suggested that such neurons could be the basic units of an information processing model of the mind.

This was a big step forward, as it suggested a potential link between the mind and brain to a science that was trying to break free from previous behaviourist ‘stimulus-response’ theories, by adopting a computational framework.

This broad approach is now the dominant theory in modern psychology, although Pitts’ was convinced of a more strictly logical model than is generally accepted today.

Pitts was completely absorbed in his work and often seemed troubled when not focused on it. It was rumoured he may have suffered from schizophrenia on account of his markedly odd behaviour and difficulties with social interaction.

Pitts moved to work with a research group in Boston, but fell out with another group member who had a disagreement with Pitts’ mentor Warren McCulloch. Pitts became a recluse and it has been rumoured he committed suicide.

Many artificial neural networks are based on his work, which are used as theoretical models of the mind, and to solve practical problems in technology and industry.

Link to Cabinet article on Walter Pitts.
Link to Wikipedia article on Walter Pitts.