Why you’ll never see hypnosis on TV, hopefully

A TV watchdog has ticked off Australian company Channel Nine for breaching the broadcasters code of conduct and showing a hypnosis session.

You may not be aware, but in many countries any broadcast of a hypnosis session is banned. Here is the relevant rule from the regulations [pdf] from the British TV watchdog Ofcom:

Rule 2.9 Hypnosis

Elements of the hypnotist’s routine may be broadcast to set the scene. However, it is important not to broadcast the routine in its entirety, nor to broadcast elements that may cause a member of the audience to believe they are being influenced in some way.

This is because it is perfectly possible to be hypnotised through the TV, or indeed through the radio.

There is no ‘magic’ to hypnosis, it just requires that someone relax, focus, listen to suggestions and engage with the process, and some research suggests that even the relaxing and focusing is optional.

The most important thing to know about hypnosis is that people vary in their hypnotisability and this is the single most important thing that determines whether suggestions will have an effect.

As long as they are spoken clearly, it doesn’t seem to matter how they’re presented.

In fact, one of the most widely used measures of hypnotisability in the scientific literature takes participants through a number of hypnotic suggestions to see which they can experience and is usually just run from a pre-recorded tape.

Link to ABC news ‘Nine attempted to ‘hypnotise viewers’ (thanks David!).

Profile of quiet revolutionary Aaron Beck

Aaron Beck is the creator of one of the world’s most widely used and influential psychological treatments, cognitive behavioural therapy, and he’s profiled in an excellent article for The American Scholar.

While Beck is most associated with CBT, the article really nails why he is important in the development of psychological treatment, and its not just for the therapy he invented: from the very beginning he scientifically tested the effectiveness and principles his treatment meaning it has constantly changed and developed according to a solid research base.

If this seems obvious to you, you need to understand a little about the history of psychotherapy before Beck applied systematic testing to his own invention.

Previously, changes in psychotherapy were largely driven by the persuasiveness and personalities of the leading lights rather than systematic evidence for effectiveness.

In many forms of therapy, especially Freudian-inspired schools, the therapist’s own personality was considered to be intimately tied up with their methods, theories and techniques, meaning that rubbishing someone’s approach also meant you were rubbishing their skill as a therapist and, often, them personally.

In the early days of psychoanalysis, a common put-down used by Freud and his disciples was that a theory they didn’t like was bad because it was tainted by the unresolved conflicts of the author. The problem, in other words, was not with the idea, but with the author.

Beck approached psychological treatment with scientific tools and immediately distanced the practice from the personal. Ideas could be put forward, tested and it was expected that many of them would fail in the face of the data.

As a result, critical reviews of the evidence are considered the life blood of the treatment.

This research-led approach has not arrived without ruffling a few feathers. Recently, as health services have decided only to fund evidence-based treatments, CBT has become the treatment of choice and other therapies have been pushed out as they’ve traditionally not been interested in doing systematic studies.

As a result, critics have argued that CBT has been moulded to fit health economics rather than human nature. The debate continues and is likely to continue for some time.

The American Scholar article is an engaging piece looking at Beck himself, a famously reserved character in the flamboyant world of therapy, and the development of his treatment.

Incidentally, it’s written by Daniel Smith who wrote the wonderful book on hearing voices called Muses, Madmen and Prophets that I highly recommend.

Link to American Scholar article ‘The Doctor Is In’.

A kick in the guts for Parkinson’s disease

Your gut has its own neural network. Called the enteric nervous system, it controls digestion and has as many neurons as the spinal cord.

Parkinson’s disease is a brain disorder that has been long associated with stomach upsets. These were often explained away as due to poor diet or stress, but it seems increasingly likely that the disease may also be affecting the neurons in the digestive system.

It was originally thought just to destroy dopamine neurons in a deep brain structure called the nigrostriatal pathway, an effect which causes the distinctive movement problems, but it has become clear that the disorder causes damage throughout the nervous system via the formation of protein clumps called Lewy bodies.

A new article in European Journal of Neuroscience suggests that Parkinson disease affects the enteric nervous system, which might tie together some curious findings in the medical literature that have remained unexplained for many years.

Stomach upsets, swallowing and digestion problems have long been associated with Parkinson’s but it has never really been clear why.

While we commonly think of it purely in mechanical terms, digestion is remarkably complex process and the enteric nervous system is involved in the careful regulation of the muscle ripples of the gut, secretion of digestive fluids and blood flow to aid absorption.

Damage to this system would cause exactly the sorts of problems that have been reported in Parkinson’s disease patients and this fits with some previous findings that have been ignored for many years.

Until recently, only one study had investigated whether the enteric nervous system was damaged in Parkinson’s patients. It found that large numbers of the gut’s dopamine neurons seemed to be missing in patients with the disorder.

The next study appeared more than ten years later, this time looking for protein clumps in the gut of deceased patients, and found evidence that not only were these tell-tale signs present, but that the distribution suggested that neurons in the gut may be the first to be damaged.

The author of this study, neuroscientist Heiko Braak now proposes the radical idea that while we know part of the risk for Parkinson’s is genetic, maybe an environmental trigger – a virus – could get into the nervous system via the stomach, eventually triggering the brain changes that lead to the debilitating tremors and movement problems.

Link to Parkinson’s and gut nervous system article summary.

Seeing the results of surgery improves outcome

A newly published study has demonstrated the remarkable influence of beliefs on our experience of illness by showing that patients undergoing surgery to correct painful spinal tears report greater improvement if they’ve been shown the fragments of the removed disc.

The researchers, a surgical team from St George’s Hospital in London, were aware that anxiety and depression had a major influence on recovery after surgery for a type of spinal disc tear, commonly but inaccurately known as a ‘slipped disc’.

They decided to try a simple measure to help patients feel less anxious and bolster their belief that a good job had been done: the surgeons presented randomly selected patients with the removed fragments from their back.

This simple technique had a remarkable effect. Patients given a ‘souvenir’ of their operation reported greater improvement in sciatic nerve pain, lower back pain, less pins and needles sensations, less leg weakness and a reduced use of pain killers.

This study adds to the increasing evidence that beliefs have a marked impact on how the symptoms of an illness manifest themselves.

We know this is particularly the case for pain, and different beliefs about what is causing the pain and the effect it has, regardless of what the reality might be, can have a significant impact on the duration and the intensity of the pain itself.

Link to PubMed entry for surgery study (via @bengoldacre).

NeuroPod on updating ye olde brain map

The latest edition of Nature’s NeuroPod podcast has just hit the wires and has some great items on updating the Brodmann brain map, a challenge to the ‘use it or lose it’ theory of synapse formation, genetic copy and pasting in neurons and face perception in the monkey.

The first part is about a project to update the Brodmann areas, a map of the brain by different neuron structures that forms the basis of much modern neuroscience but is now 100 years old.

German neurologist Korbinian Brodmann started mapping the brain with his microscope and charting the different ways brain cells were organised and still today, if you read scientific papers on the brain, they often refer to places like Brodmann area 10 as a way of locating specific parts.

So you can see why the 100 year-old map needs an update.

Link to NeuroPod webpage.
mp3 of latest edition.

Drug smuggling innovations bulletin

I’ve just discovered the joys of the Microgram Bulletin, the newsletter of the US Drug Enforcement Administration that explains interesting new drug finds and novel methods for smuggling illicit substances.

It’s a curious mirror of the illicit drug trade and contains numerous mysterious finds, such as playground marbles systematically placed in cocaine bricks for an unknown purpose, or a find of cocaine smuggled as clear plastic-like coating for calendars, photos or magazines.

The bulletin also reports ‘mimic’ drugs, where manufacturers are passing off cheaper (and often nastier) substances as pill-based drugs such as ecstasy or amphetamine.

The publication has been going mostly monthly since 2003, and I recommend checking out some of the earlier editions as they contain some great essays and technical reports on the drug trade.

For example, there’s one edition with an analysis of cocaine trafficking derived from chemical analysis of seized drugs, and another on chemical dumps from illegal drug labs.

The picture on the left is from a report entitled “Cocaine concealed in religious plaques in Miami, Florida” from a report from May this year.

Link to DEA Microgram Bulletin online.

The automated phrenologist

I’ve just discovered the excellent This Week in the History of Psychology podcast series which has a particularly good episode on the ‘psycograph’, an automated phrenology device created in 1905.

The idea is that it would ‘read’ the bumps on your head by the use of mechanical plungers and it would then print a profile of your ‘character’ in a matter of seconds.

There’s a remarkable amount of information about this device on the web (and yes, “psycograph” is the correct spelling) including a fantastic page of original advertising.

You can download the relevant podcast as an mp3 and the others are also well worth checking out.

They are written and presented by mind and brain historian Christopher Green, who you may know from the Classics in the History of Psychology website, or his involvement with Advances in the History of Psychology blog.

Don’t be put off by the headache-inducing website, unlike many other special podcasts, is very well produced with high quality audio and an impressive line-up of researchers.

Link to This Week in the History of Psychology podcasts.

To the scent side

Photo by Flickr user SteffanyZphotgraphy. Click for sourceThe New York Times covers an interesting study finding that if you smell different odours in each nostril the brain doesn’t blend the scents, instead, your experience of smell alternates between the two.

This nostril rivalry, as the researchers describe it in a paper in Current Biology, is similar to what happens when the eyes are presented with different images, or the ears with different tones.

The researchers experimented with 12 people using two chemicals, one that has an odor like a marker pen, the other that smells like a rose. All 12 experienced switching between the two odors, with no pattern as to when and how often they switched.

And as with hearing and vision, smell sensitivity is related to the general tendency for left or right hemisphere activation in the brain.

Because this general tendency is also related to a bias for magical thinking and unusual perceptual experiences, we know that differences in nostril sensitivity can be found between people who have high numbers of paranormal-like experiences and those who don’t.

Link to NYT piece ‘How the Nose Copes With Nostril Rivalry’.
Link to PubMed entry for study.

I’ll give you a piece of my printed mind

We occasionally thrown down a few mind and brain t-shirts for you here at Mind Hacks but I’ve recently discovered a whole t-shirt label dedicated to the stuff between your ears.

The Printed Mind has a number of fantastic big graphic t-shirts dedicated to the mind and brain, and because they look so great, I think we can ignore the occasional lapse (*cough* total disregard) for anatomical correctness.

I mean, you wouldn’t want a naked lady tattoo where someone had got the anatomy wrong, so why would you want it on a t-shirt?

Maybe if it was glow in the dark?

Now you’re talking.

Link to The Printed Mind online shop (via Coty Gonzales).

2009-09-04 Spike activity

Quick links from the past week in mind and brain news:

Neuroskeptic reports on a study finding that antidepressant use in the USA has doubled in the last decade. Interestingly, peak use is in 50-64 year-olds.

There’s some organic robot art inspired by Rorschach inkblots over an Seed Magazine.

The New York Times has an excellent piece about the role of guilt in regulating behaviour in children.

The effect of our beliefs and expectations on the taste of <a href="http://www.psychologytoday.com/blog/sensory-superpowers/200908/you-drink-what-you-think
“>wine is explored in the Sensory Superpowers blog.

Science News covers a study on how baby girls more quickly associate fear with snakes and spiders than boys.

There are some interesting talks on culture and neuroscience from the Neurocultures Workshop despite the audio being a bit poor. See left hand side bar for links to video and mp3.

The New York Times has a fascinating article on projects that crawl the web and look for indicators of people’s mood, creating global emotion maps.

A new antipsychotic, named lurasidone, is likely to be hitting the market shortly, according to Furious Seasons. Promises to improve treatment of psychosis, probably won’t.

The Economist covers a study on the role of female testosterone levels in financial risk taking.

Continuing on the testosterone theme, a study covered by New Scientist finds that men with higher levels of the hormone spend less time with their children.

Neuronarrative has a fantastic post on a study finding that during a simulated crime, researchers were able to induce false confessions in nearly everyone using faked video evidence.

Another interesting study into the remarkable self-organising properties of crowds is covered by the ever excellent BPS Research Digest.

Technology Review blog covers an interesting paper arguing that measuring the entropy of reaction times within a psychology experiment may be a better way of inferring cognition.

Neuroscientist Nancy Kanwisher recently gave a keynote talk to the Association for Psychological Science and you can read or watch it via The Situationist.

New Scientist covers an absolutely fascinating study that looked at how different types of dementia break down the small world network of the brain’s neural architecture in specific ways.

There’s an interesting review of studies on how written language style earlier in life can predict the chance of getting Alzheimer’s disease when older at Language Log.

Culture Matters has an interesting post about cultural differences in attitudes to sexual aids like Viagra and penis enlargers in the Arab world.

The not so grateful dead

Photo by Flickr user Zach K. Click for sourceIf you suddenly find your web filter is blocking Mind Hacks, it’s because this post is about necrophilia. A paper just published in the Journal of Forensic and Legal Medicine has proposed the first classification of sexual attraction to death and the dead.

I maintain an amateur interest in the forensic psychology literature because there is nothing that lays out the full range of human behaviour in such stark contrast and nothing which will challenge your assumptions about the things society feels least comfortable talking about.

This paper is a good example. You can probably think of nothing more revolting than necrophilia but the review makes clear that the link between sexual arousal and death can include consenting adults acting out B-movie fantasies to people who are unable to get aroused except by anything corpses, with almost everything in between.

Apparently, there was previously too little research in the area to allow a coherent classification of the different types and this is the first paper that attempts to map the range of sexual attraction to death.

There is nothing gratuitous in the article and it is a seriously scholarly piece, but if you’re not comfortable with some of the darker corners of human existence you may find it hard going.

Link to paper on the classification of necrophilia.
Link to PubMed entry for same.

Supratentorial

I was told of this funny bit of medical jargon yesterday by a psychiatrist friend of mine, which, apparently, is occasionally used by physicians when they want a medical sounding way of saying that the patient’s symptoms exist only in their imagination.

Luckily I found a great definition on Urban Dictionary:

Supratentorial

A word used by doctors and nurses to imply that a patient’s problems are all in their mind. The tentorium is a membrane just under the brain, so “supratentorial” refers to what is above that, namely the brain. This term can be used in front of the patient or patient’s family because it sounds like technical jargon.

Patient: “Every time Dr Phil comes on TV, my arms and legs start twitching!”

Doctor, quietly to nurse: “Seems to be a supratentorial problem.”

Then to patient, condescendingly: “Sorry, dear, we’re just talking shop. Go on.”

Link to Urban Dictionary definition (thanks Quinton!)

Zombie brain cupcakes

Photo by Flickr user xsomnis. Click for sourcexsomnis is a Flickr user with a passion for the patisserie who has made these wonderful brain cupcakes for the next time you have some distinguished zombies round for afternoon tea.

She’s even created a Flickr set that explains how to make the sweet brain toppings.

They almost look too good to eat. Unless you’re undead of course.

Link to zombie brain cupcakes.
Link to brain topping instructions.

Placebo has strength in numbers

Photo by Flickr user anitacanita. Click for sourceWired has an excellent article on how the placebo effect is increasing in drug trials and how drug companies are trying to understand why. It’s an intriguing article but it conflates two distinct concepts of ‘placebo’ that need to be separated to fully understand the effect.

The term ‘placebo effect’ is used to refer to two things in the medical literature. The first is a statistical concept and it refers to the improvement in patients given an inactive treatment in a drug trial in comparison to those given the actual drug. The second is a psychological concept and it refers to improvement due to expectancy and belief.

If you’re not sure how these are different, you may be surprised to learn that you don’t need a mind to demonstrate the placebo effect – in fact, even rocks can show it.

Let’s say an oil tanker has sunk, the local beach is covered in oil, and you want to compare how effective two cleaning products are – the first, liquid soap, our active treatment, and the second water, our placebo.

So we randomly assign oily stones to a bucket of soapy water or to a bucket of water. It turns out that while stones in the soap condition become less oily, so do stones in the placebo condition, although, perhaps, the effect is weaker. Oil breaks down on its own, water movement disperses it, oxygenation happens. There’s a whole bunch of stuff which means our placebo ‘treats’ the stones.

Statistically we have a placebo effect, because in a trial anything which causes improvement not to do with the active treatment is chalked up to the placebo effect.

In humans, similar effects are at work. Most illnesses improve on their own, when we catch anything at its worst typically it will return to its normal state (an effect known as regression to the mean), people change their behaviour to become more healthy when they’re ill, and so on. None of these are to do with expectancy or beliefs about taking a pill.

But here’s the other thing. Because the statistical concept of placebo is drawn from the study data, the study itself has an effect.

For example, the strength of the placebo effect is measured relative to the active treatment. The Wired article says that placebo is getting stronger, which is another way of saying that the difference between placebo and the drug is getting smaller.

It turns out that the more rigorous the study the less strong the drug effect is, or, in other words, the stronger the placebo effect.

For example, we know that better designed and higher quality studies show smaller drug effects. This includes things as simple as randomisation. If your method for randomly allocating people to groups is more susceptible to bias, it’s more likely to produced biased results. Better randomisation improves the placebo effect, again, nothing to do with expectancy or belief.

So one reason why the placebo effect might be increasing is that studies are just more rigorous these days.

Of course, on top of all of these things, individual psychology plays a part as it adds improvement, and anything which leads to improvement gets captured by the statistical placebo effect.

However, the lab-based studies which investigate placebo look almost exclusively at the psychological placebo effect. They examine the effects of beliefs and expectations but usually carefully control the presence of the unpleasant thing, like pain, so it doesn’t naturally improve and you can’t change your behaviour like you would in real life.

You can’t explain the statistical placebo effect just with psychology. It’s part of it, but not the whole story.

So when I read the article which said that drug companies are busily doing lab studies to understand why the placebo effect is increasing I became a bit suspicious.

The first thing you’d do is look at how your studies have been run, not look at the psychology of belief. Drug companies undoubtedly know this. They’re masters of drug trial sleight-of-hand and know research methods inside out.

The article touches on a likely explanation – marketing. They would like to influence your beliefs so the drug works better for you, because once it’s on the market, it’s the customers’ experience that brings them back for more.

In an industry where genuinely new drugs are rare and most are just no-better copies of rival medications, your beliefs could make all the difference.

Link to Wired on the increasing placebo effect.
Link to previous Mind Hacks post on the psychology of placebo.

The sexual transformation delusion

Photo by Flickr user jcoterhal. Click for sourceMedical journal Epilepsy and Behavior has a curious case study of a female patient who had the experience of changing sex when she had a seizure.

The patient in question had a small tumour near the right amygdala and showed abnormal right temporal lobe activity on an EEG. Interestingly, when she had the experience of changing sex, she also experienced other females in the vicinity as also transforming into males.

She experienced a sensation of dull nausea rising from the epigastrium [abdomen] with concomitant fear, sometimes also accompanied by déjà vu, in isolation, several times per week. Occasionally this developed into a complex alteration of perception, which she explained as follows: ”I’m no longer feeling to be a female. I have the impression to transform into a male. My voice, for example, sounds like a male voice that moment. One time, when I looked down to my arms during this episode, these looked like male arms including male hair growth.”

This particular kind of perceptual disturbance was not restricted to herself, but also characterized her perception of female persons nearby during the episode: “One time another woman, a friend of mine, was in the same room, I perceived also her as becoming a male person including changing sound of her voice.” After introduction of anticonvulsive treatment with carbamazepine, only the elementary simple-partial phenomena of epigastric aura and déjà vu persisted. Secondary generalized tonic–clonic seizures never occurred.

Sex change delusions have been reported in the medical literature before, but usually in longer-term psychoses in people with diagnoses like schizophrenia, rather than occurring as a short-term effect of a seizure.

In fact, sex change delusions were reported by one of the most famous psychiatric patients in history: Daniel Schreber, a 19th century German judge who wrote about his experience of insanity in his book Memoirs of My Nervous Illness.

Among other experiences he describes how he believed that his mind was attracting ‘rays’ from God causing him feminising sensations of ‘voluptuousness’ which he noticed as female body changes.

Temporary sex change ‘delusions’ have also been created using hypnosis in highly hypnotisable people in two remarkable studies that attempt to understand how the mind justifies a belief clearly contrary to reality.

Link to DOI entry and summary of case study.

Ten year high

Photo by Flickr user MyDigitalSLRCamera. Click for sourceOriginally an academic project to study the science of happiness, positive psychology has spawned a hippy fringe of life coaching and self-help. In a thoughtful review of the field, The Chronicle of Higher Education looks at the state of the elation after its first decade in existence.

Positive psychology maintains a core of rigorous empirical science but it is clear from the article that there is considerable tension between those who simply want to investigate the building blocks of the good living and those who want to extend (and sometimes over-extend) the work into life guidance.

Although it has gained considerable respectability, the field is still treated with suspicion in some corners of mainstream psychology, not least because of the tendency for academia to privilege austere seriousness and to treat anything with mass appeal with elitist disdain.

But still there is a slightly evangelical feel to positive psychology which make some people uncomfortable.

Two of the field’s founders and most enthusiastic proponents became famous for some of the darkest and bleakest studies in psychology: Martin Seligman’s work on depression and learned helplessness was based on how some dogs give up trying to escape when repeatedly tortured with inescapable electric shocks and Philip Zimbardo’s prison experiment showed that respectable people can be turned into brutal abusers when the context encourages it.

Whether Seligman and Zimbardo feel they’re repenting for their dark past or not, many who associate with the field have the zeal of those reborn from a science previously obsessed with human misery.

The Chronicle article is a insightful look into both the science and culture of positive psychology, taking a particularly close look at the tensions which are shaping how we understand human growth and potential.

Link to Chronicle on 10 years of positive psychology (via @researchdigest).