Five minutes with Howard Dully

howard_dully.jpgDave Isay, Piya Kochhar and Howard Dully produced one of the most powerful radio documentaries of 2005 where Howard told the story of his own lobotomy and the quest to make sense of the experience.

A lobotomy is a type of brain surgery to disconnect parts of the frontal lobes from the rest of the brain.

It was originally devised by Egas Moniz as a treatment for psychiatric illness because it seemed to have a ‘calming’ effect.

Howard was given the operation when only 12 years old by Walter Freeman – the world’s most enthusiastic evangelist for this procedure.

The procedure is now almost entirely disused, owing to the poor outcomes and dangers of the procedure, but it has left a legacy of people with permanently altered lives.

Howard wanted to understand how this dangerous procedure came to be so widely used and how it came to be performed on him as a child. He has also been kind enough to talk to Mind Hacks about his experiences.

Continue reading “Five minutes with Howard Dully”

Our memory is our coherence

“You have to begin to lose your memory, if only in bits and pieces, to realize that memory is what makes our lives. Life without memory is no life at all, just as an intelligence without the possibility of expression is not really an intelligence. Our memory is our coherence, our reason, our feeling, even our action. Without it, we are nothing.”

The legendary surrealist Spanish filmmaker Luis Buñuel on the existential importance of memory. Thanks Katerina!

A Whiter Shade of Searle

The Boston Globe has a brief interview with philosopher John Searle where he’s quizzed about his views on consciousness, computation and consensus.

Despite having a back catalogue stretching back to the 60s, prog rock band Procol Harum are popularly remembered as ‘the band who did A Whiter Shade of Pale’.

Similarly, despite his wide-ranging work, Searle is popularly remembered as the ‘guy who devised the Chinese room argument’.

Searle is the Procol Harum of philosophy, although, to be fair, his back catalogue is actually worth checking out.

In this interview with the Globe’s Ideas section, he touches on consciousness, free will, whether the mind can be described as computation, and why philosophers disagree so much.

IDEAS: You think that questions about the mind are at the core of philosophy today, don’t you?

SEARLE: Right. And that’s a big change. If you go back to the 17th century, and Descartes, skepticism — the question of how it is possible to have knowledge — was a live issue for philosophy…

IDEAS: Why the change?

SEARLE: We know too much. The sheer volume of knowledge has become overwhelming. We take basic findings from physics and chemistry about the universe for granted. Knowing much more about the real world than our ancestors did, we can’t take skepticism seriously in the old way. It also means that philosophy has to proceed on the basis of all that we know.

The universe consists of matter, and systems defined by causal relations. We know that. So we go on to ask: To what extent can we render our self-conception consistent with this knowledge? How can there be consciousness, free will, rationality, language, political organization, ethics, aesthetics, personal identity, moral responsibility? These are questions for the philosophy of mind.

Link Q&A with John Searle from The Boston Globe (via 3Q).

Overlooking infinity

“From my fourth-floor room overlooking infinity, in the viable intimacy of the falling evening, at the window before the emerging stars, my dreams – in rhythmic accord with the visible distance – are of journeys to unknown, imagined or simply impossible countries.”

Text 421 (‘Journey in the Mind’) from The Book of Disquiet (ISBN 0141183047) by Portuguese poet Fernando Pessoa.

Eric Kandel profiled

There’s a great introductory profile of psychiatrist and neurobiologist Eric Kandel in Columbia Magazine that outlines his life and Nobel-prize winning work.

Kandel is best known for his work on how memory operates at the cellular and molecular level.

For example, his research has investigated long-term potentiation, the process by which the synaptic connection between neurons is temporarily strengthened.

This has been cited as the basis of neural plasticity – the process by which the brain can re-organise itself at the cellular level to make new connections and pathways.

This is thought to be essential for learning, as well as recovery after damage.

Kandel’s “new science of mind” is an integration of neuroscience, biology, and the study of behavior that will connect the workings of individual neurons in the brain with philosophy, sociology, economics, art, war, and manifestations of human culture. “Neuroscience is the Esperanto,” Kandel says, “the humanistic language that binds it all together.” His research into the molecular and cellular basis of short- and long-term memory forms the foundation for the understanding of this language. His work illuminating how signals move through neurons earned him the Nobel Prize in Physiology or Medicine in 2000, alongside Arvid Carlsson from the University of G√∂teborg in Sweden and Paul Greengard of Rockefeller University. Kandel is, as Grundfest suggested 50 years ago, taking the next step in the study of the mind. “I think it’s likely that a variety of social phenomena are going to be explored at the biological level,” he says.

Kandel is also well-known for being the first author of the weighty neuroscience ‘bible’ Principles of Neural Science (ISBN 0838577016).

UPDATE: A video and transcript of Kandel’s Nobel lecture is available here. Thanks Mxr!

Link to article ‘Minding the Brain’.

The buzzing blooming life of William James

The Boston Globe has a review of a new biography of William James. He is often called the ‘father of modern psychology’ and is equally well-known for his work in philosophy.

Not quite as well-known is his drug-experimentation, fascination with parapsychology and interest in numerous women.

It’s almost a clich√© that psychology talks will start with a quote from James. Largely because his work, most notably the book The Principles of Psychology, touched upon almost every area now part of mainstream cognitive science.

His interests were truly eclectic, however, and his writing explores a diverse range of thoughts and experiences.

One of my favourite James quotes is a sentence he wrote after taking nitrous oxide (‘laughing gas’), recorded in an essay on the experience:

“There are no differences but differences of degree between different degrees of difference and no difference.”

James also experienced terrible depressions and suicidal thoughts throughout his life, giving him first hand experience of a mind gone awry.

Perhaps a combination of natural curiosity and an interest in altered states led James to radical and still-influential theories of mental life.

A recent review from The New York Times summed it up like so:

It is hard to maintain the illusion of the disembodied philosopher in the face of this larger-than-life and fascinatingly cracked personality, who pragmatically turned the very fissures of his soul into metaphysical positions.

There’s more in the reviews, and the book itself, William James: In the Maelstrom of American Modernism (ISBN 0618433252), has recently hit the shelves.

Link to Boston Globe review of James biography (via 3Q).
Link to review from LA Times.
Link to extensive review from The New York Times.

A Madman Dreams of Turing Machines

Some dialogue from the novel A Madman Dreams of Turing Machines (ISBN 1400040302) by physicist Janna Levin.

In this passage, Kurt G√∂del discusses his objections to Alan Turing’s work on whether the mind can be completely described as a series of computations with his friend Oskar Morgenstern.

“If I die, you must promise to publish my article refuting Alan Turing’s thesis on the limitations of the mind. A Turing machine is a concept, equivalent to a mechanical procedure or algorithm. Turing was able to completely replace reasoning by mechanical operations on formulas – by Turing machines. Good, agreed?

However, are we supposed to equate the human soul with a Turing machine? No. There is a philosophical error in Turing’s work. Turing in his 1937 paper, page 250, gives an argument which is supposed to show that mental procedures cannot go beyond mechanical procedures. However this argument inconclusive. What Turing disregards completely is the fact that mind, in its use, is not static but constantly developing.

They murdered him, you realize?”

“I thought it was suicide,”, Oskar replies absently.

Kurt continues, “The government poisoned his food. I have also been working on a formal proof of the existence of God. But this is unfinished. I don’t want our colleagues to think I am crazy. Maybe you should not published that one if I die.”

Gödel eventually died from starvation, owing to paranoid beliefs about conspiracies and poisoning.

G√∂del’s idea that consciousness is not understandable as a form of computation was further developed by mathematician Roger Penrose in the book Shadows of the Mind (ISBN 0198539789).

Link to excerpt from book.
Link to Janna Levin’s website.

Light sleep

A poem on the collective unconsciousness of sleep by British poet John Hegley:

Light Sleep

Early in the evening I like to have a kip and dip
into the pool of communal unconcious;
resting, passive,
where whatever size of a drip you are
you make the whole
more massive.

Hegley’s poems are a mixture of the whimsical, insightful and touching. We’ve featured the Hegley poem ‘Outsider art’ previously on Mind Hacks.

The woman who thinks like a cow

Google Video seems to have the full length documentary on Prof Temple Grandin, a world expert on animal science who was diagnosed with autism as a child.

As well as her academic work which has been hugely influential around the world, she has also written several books on the psychology of autism that have become widely read by professionals and the public alike.

Her story first became known as she was included as a case study in neurologist Oliver Sacks’ book An Anthropologist on Mars.

Interestingly, Grandin suggests that her autism helps her understand animals, as she suggests they have similar styles of thinking in some instances.

In the programme, Grandin explains her work and views on autism. Furthermore, the documentary highlights her as a bright and engaging person, far from the usual stereotypes of autistic people.

Link to video of ‘The Woman Who Thinks Like a Cow’.
Link to Prof Temple Grandin’s website.

Phineas Gage and the rod of iron

The Neurophilosopher has written a great introduction to the history and science of Phineas Gage – one of the most famous cases in the history of neurology.

In 1848, Gage was a railroad worker who had the sort of job that sounds like it was designed for the Darwin awards: he was paid to drill holes in large rocks, fill them with gunpowder and pack it down with a large iron rod.

Not surprisingly, the gunpowder eventually ignited, sending the tamping iron through Gage’s skull.

Remarkably, Gage survived, but not without significant damage to his frontal lobes.

Gage seemed to show some changes in character (although the exactly details are still somewhat controversial), and this was one of the first clues that specific areas of the brain may be involved in specific mental functions.

More recently, scientific studies have been completed to work out the path of the iron through his skull, to understand exactly how the brain was affected.

Neurophilosopher has video of the computer reconstructions created by these studies, and discusses some of the historical details of the incident.

Link to ‘The incredible case of Phineas Gage’.
Link to Wikipedia page on Phineas Gage.

What caused Nietzsche’s insanity and death?

A paper just published in Acta Psychiatrica Scandinavica reconsiders the insanity and death of philosopher Friedrich Nietzsche, who is commonly thought to have died of neurosyphilis.

In contrast, the authors of the new study suggest that Nietzsche died of frontotemporal dementia – a type of dementia that specifically affects the frontal and temporal lobes.

While many people have ‘diagnosed’ historical figures in retrospect, this study is different, in that the authors reviewed Nietzsche’s actual medical notes in light of what is known about the progression of syphilis and dementia today.

More than 100 years after his death, Friedrich Nietzsche remains one of the most contentious figures in the history of philosophy. His writings contain some of the most profound philosophical statements of the 19th century, and have been exceptionally influential. However, they also express ambiguities and contradictions, which leave scholars perplexed and still arguing about their meaning and intent. Such ambiguities are reflected not only in Nietzsche’s life, but also in his terminal illness and death.

Following a psychotic breakdown in 1889, at the age of 44 years, he was admitted to the Basel mental asylum and on 18 January 1889 was transferred to the Jena mental asylum. He remained in demented darkness until his death on 25 August 1900. In Basel, a diagnosis of general paralysis of the insane (GPI; tertiary cerebral syphilis) was made. This diagnosis was confirmed in Jena and is still widely accepted. However, even some of Nietzsche’s contemporaries doubted this. The lack of certainty about his primary luetic infection, the long duration of the disease and some clinical features lead us to question the diagnosis of GPI.

In this study, we re-construct the anamnesis [clinical history] of Nietzsche’s illness and review the clinical presentation. We then note the natural history of GPI as it was at the turn of the 19th century, and suggest an alternative diagnosis, namely that of frontotemporal dementia (FTD) which has been characterized in detail only in the last two decades.

Link to abstract of paper.

Five minutes with Nick Yee

Nick Yee is researching the psychology of social interaction in online worlds, and finding some surprising results.

At first sight, multi-player worlds like Second Life and World of Warcraft may seem like relatively crude or whimsical simulations of real-life social situations.

But intriguingly, Yee has discovered that ‘personal space’ and other aspects of non-verbal communication are just as important, and that offline romances can blossom in online game worlds.

While these worlds are becoming the centre of new economies, social groups and leisure activities, Yee hopes to understand how the human mind adapts to communication via virtual reality.

He’s also kindly agreed to talk to Mind Hacks about his work and latest discoveries.

Continue reading “Five minutes with Nick Yee”

Psychology art gallery

face_town.jpgPsychology lecturer and author Gerard Keegan has created a fascinating website of psychology curios, including a ‘psychology art gallery‘ that contains a number of visual illusions or images that play with the limits of our visual perception.

Keegan is the author of Higher Psychology a textbook for 16-18 year-old psychology students and his site shows a similar passion for communicating psychology in a straightforward and accessible manner.

Link to psychology art gallery.